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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FYN
All Species:
31.82
Human Site:
S257
Identified Species:
70
UniProt:
P06241
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06241
NP_002028.1
537
60762
S257
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Chimpanzee
Pan troglodytes
XP_001158656
541
61057
S261
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Rhesus Macaque
Macaca mulatta
XP_001085015
537
60711
S257
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Dog
Lupus familis
XP_854467
537
60713
S257
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Cat
Felis silvestris
Mouse
Mus musculus
P39688
537
60637
S257
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Rat
Rattus norvegicus
Q62844
537
60683
S257
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505504
656
73783
V376
S
N
Y
T
P
Q
T
V
G
L
S
K
D
A
W
Chicken
Gallus gallus
Q05876
534
60247
V254
T
N
N
T
P
Q
T
V
G
L
A
K
D
A
W
Frog
Xenopus laevis
P13406
537
60828
S257
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Zebra Danio
Brachydanio rerio
NP_001025140
544
61022
S264
M
P
R
L
T
D
L
S
V
K
T
K
D
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
Q258
V
R
K
L
G
S
G
Q
F
G
D
V
W
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.6
99.8
N.A.
99
99.6
N.A.
70.1
92.3
96.8
90.6
N.A.
54.5
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
99.8
99.8
N.A.
99.6
99.6
N.A.
73.3
94.4
98.1
95.2
N.A.
68.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
20
100
100
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
20
100
100
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
73
0
0
0
0
10
0
91
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
19
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
73
0
91
0
0
0
% K
% Leu:
0
0
0
82
0
0
73
0
0
19
0
0
0
0
0
% L
% Met:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
73
0
0
19
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
19
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
10
73
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
0
73
0
0
10
0
0
0
0
% S
% Thr:
10
0
0
19
73
0
19
0
0
0
73
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
19
73
0
0
10
0
73
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
91
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _